
Ipamorelin
Ipamorelin
Growth Hormone Release • Recovery • Fat Loss • Sleep & Repair


Benefits of Ipamorelin
Fat Loss & Metabolic Improvements
Increased lipolysis (fat burning)
Reduced abdominal & visceral fat
Improved metabolic rate
Better insulin sensitivity
Muscle Repair & Recovery
Faster healing from training
Enhanced collagen formation
Improved strength gains
Better connective tissue repair
Sleep, Mood & Cognitive Improvements
Deeper restorative sleep
Reduced nighttime waking
Better mood regulation
Sharper mental clarity
Anti-Aging & Longevity
Improved skin elasticity
Enhanced cellular repair
Healthier hair and nails
How Ipamorelin Works (Mechanisms of Action)
1. Binds to GHS-R1a Receptors
Ipamorelin activates the growth hormone secretagogue receptor (GHS-R1a), located in the pituitary gland and hypothalamus.
This stimulates natural GH release while preserving your biological rhythm.
2. No Prolactin or Cortisol Elevation
Unlike older peptides (GHRP-6, GHRP-2):
Ipamorelin does NOT increase cortisol
Does NOT increase prolactin
Does NOT stimulate ghrelin hunger spikes
This makes it one of the cleanest GH secretagogues available.
3. Boosts GH → Increases IGF-1
Growth hormone and IGF-1 support:
tissue healing
fat breakdown
muscle growth
recovery
skin rejuvenation
4. Improves Deep-Wave Sleep
GH peaks during deep sleep.
Ipamorelin enhances:
sleep quality
REM cycles
physical recovery
growth hormone pulsatility
Many clients report stronger sleep within 1–2 weeks.
What Is Ipamorelin?
Ipamorelin is a highly selective growth hormone secretagogue (GHS)—one of the safest and most widely used peptides for enhancing recovery, fat loss, sleep, and cellular repair.
Known for its clean profile (no cortisol or prolactin elevation), Ipamorelin mimics your body’s natural signaling to gently increase pulsatile GH release.
It is ideal for clients seeking:
recovery from training
fat reduction
deep restorative sleep
enhanced repair
healthy aging
improved muscle tone
It is commonly stacked with CJC-1295 DAC for amplified effects.




Dosage, Injection Volume & Cycling
Concentration:
10 mg / 10 ml (1 mg/ml)
Dose:
100–300 mcg (0.1–0.3 mg)
1–2× daily
Injection Volume:
100 mcg = 0.1 ml SC
300 mcg = 0.3 ml SC
Synergy Stacks
Ipamorelin + Epithalon
For anti-aging, sleep, longevity.
Ipamorelin + Retatrutide
For metabolic transformation + recovery.
CJC-1295 DAC + Ipamorelin (Most Popular)
Maximises GH pulses, recovery, fat burning, and sleep.
All treatments include a brief consultation and are supervised by qualified clinicians.
Who Is Ipamorelin Ideal For?
Great for clients who want:
Recovery boosting
Body recomposition
Better sleep
Hormone optimization
Anti-aging support
Stress resilience
Post-injury recovery
Safe for both men and women.
Cycle:
12 weeks on → 4 weeks off
Injection Sites:
Abdomen
Upper thigh
Glute
Rotating weekly
Timings:
Morning (fat loss)
Pre-bed (sleep + recovery)
Pre-training (performance)
Ipamorelin + BPC-157
For injury recovery + connective
tissue repair.
Safety & Side Effects
Extremely safe and well tolerated.
Possible mild effects:
Temporary flushing
Mild water retention
Tingling or warmth
Injection site redness
Avoid in:
Pregnancy or breastfeeding
Uncontrolled cancer
Ipamorelin — Scientific Research & Clinical Studies
Foundational pharmacology of Ipamorelin – Describes Ipamorelin as a selective GH secretagogue with high potency and low off-target endocrine effects. PubMed+1
https://pubmed.ncbi.nlm.nih.gov/9849822/
https://www.semanticscholar.org/paper/Ipamorelin%2C-the-first-selective-growth-hormone-Raun-Hansen/67208f356c5d77afd1359cf90a9fdb88bfe7e794
Oral GHS derived from Ipamorelin analogue – Discusses ghrelin receptor agonists and derivatives (including Ipamorelin-based peptidomimetics) as GH secretagogues. PubMed
https://pubmed.ncbi.nlm.nih.gov/11322495/
Review on GH secretagogues & ghrelin agonists – Summarises clinical and mechanistic data on GH secretagogues (GHS), including Ipamorelin-class compounds. PMC+1
https://pmc.ncbi.nlm.nih.gov/articles/PMC7108996/
https://onlinelibrary.wiley.com/doi/full/10.1002/rco2.9
Clinical Disclaimer
This information is derived from clinical research, peer-reviewed studies, and scientific literature. Peptides are provided at The NAD Clinic for research and therapeutic use under medical supervision. They are not intended to diagnose, treat, or cure medical conditions.



