TB-500 (Thymosin Beta-4)

TB-500 (Thymosin Beta-4)

Advanced Tissue Regeneration • Anti-Inflammatory Repair • Injury Recovery • Synergy With BPC-157

Benefits of TB-500

 Musculoskeletal Repair

• Tendon & ligament tears

• Rotator cuff injuries

• Knee, elbow, shoulder degeneration

• Chronic tendonitis

• Plantar fasciitis

• Golfers/tennis elbow

• Hip and groin injuries

 Sports Recovery

• Faster recovery from training

• Reduced DOMS

• Support for high-volume or high-load athletes

 Anti-Inflammatory

• Chronic inflammation

• Joint stiffness

• Fascia restriction

 Neuroprotective

• Supports nerve healing

• Useful for impingement-related pain

• Assists in neuropathic injury recovery

 Post-Surgery

• Accelerates surgical healing

• Reduces scar tissue

• Restores mobility

How TB-500 Works (Mechanisms of Action)

 1. Regulates Actin Cytoskeleton

TB-500 increases actin (a key protein involved in cell structure and movement).
This accelerates:

• Cell migration to injury sites

• Tissue repair

• Fascia, ligament, and muscle healing

Actin regulation is the core mechanism behind TB-500’s speed of healing.

 2. Enhances Angiogenesis

TB-500 promotes new blood vessel formation, improving:

• Blood flow

• Oxygen delivery

• Nutrient transport

• Waste clearance

Essential for healing tissues with poor blood supply (tendons, ligaments, cartilage).

 3. Potent Anti-Inflammatory Effects

TB-500 reduces:

• Pro-inflammatory cytokines

• Oxidative stress

• Fibrosis development

This helps calm chronic injuries and expedite recovery.

 4. Supports Nerve Repair

Studies show TB-500 supports nerve regeneration via improved:

• Schwann cell activity

• Myelination

• Axonal repair

Useful for nerve impingements, neuropathy, and chronic back injuries.

 5. Synergistic With BPC-157

Together they form the strongest healing duo in regenerative medicine:

• TB-500 = systemic healing & angiogenesis

• BPC-157 = local repair & collagen alignment

What Is TB-500?

TB-500 is a synthetic version of Thymosin Beta-4, a naturally occurring regenerative peptide found in nearly all human cells.
It plays a critical role in:

• Cell migration

• Blood vessel formation (angiogenesis)

• Tissue repair & remodeling

• Inflammation reduction

TB-500 is particularly valued for treating structural injuries — tendons, ligaments, fascia, cartilage, muscles, and even nerves.
It is one of the most powerful systemic healing peptides available and is often stacked with BPC-157 for maximal results.

Dosage, Injection Volume & Cycling

 Concentration:

20 mg / 10 ml (2 mg/ml)

 Dose:

Loading Phase (Weeks 1–6)
2–5 mg twice weekly

• 2 mg = 1 ml

• 5 mg = 2.5 ml

 Injection Volume:

• 2 mg → 1 ml SC

• 5 mg → 2.5 ml SC

Synergy Stacks

 Ultimate Healing Stack

• TB-500 + BPC-157
  → Fastest tissue repair combination.

 Anti-Inflammatory Repair

• TB-500 + KPV

 Performance Recovery Stack

• TB-500 + NAD+
  → Faster recovery, less inflammation, improved cellular repair

All treatments include a brief consultation and are supervised by qualified clinicians.

Who Is TB-500 Ideal For?

 Athletes & Gym-Goers

• Recurrent tendon problems

• Soft tissue injuries

• Joint/ligament degeneration

 Older Adults

• Chronic stiffness

• Reduced healing capacity

• Post-surgical recovery

 Injury Rehab Cases

• Meniscus issues

• Rotator cuff tears

• Back, knee, hip injuries

• Fascia pathology

 Cycle:

6–8 weeks on / 4 weeks off

 Injection Sites:

• Subcutaneous (SC) or Intramuscular (IM)

• Rotate injection sites

• Can inject near injury site

 Post-Surgery Rehab

• TB-500 + BPC-157 + Vitamin infusions (ALA, Taurine, Glycine, B12)

 Safety & Side Effects

Generally extremely well tolerated.
Possible temporary reactions:

• Mild headache

• Slight fatigue

• Injection site redness

• Increased appetite (rare)

• Transient lightheadedness

No known major adverse reactions in clinical studies.

 Chronic Pain Patients

• Long-standing inflammation

• Restricted mobility

 Nerve-Related Clients

• Sciatica

• Neural inflammation

• Post-injury nerve repair

 TB-500 / Thymosin β4 — Scientific Research & Clinical Studies

• Thymosin β4 accelerates wound healing – Rat full-thickness wound model showing significantly faster re-epithelialisation and wound contraction with Tβ4. PubMed
  https://pubmed.ncbi.nlm.nih.gov/10469335/

• Collateral ligament and tendon/skin healing – Studies report improved collagen organisation and enhanced ligament and wound healing with Tβ4 administration. ScienceDirect
  https://www.sciencedirect.com/science/article/pii/S0167011513000645

• Regenerative/anti-aging review on Thymosin β4 – Explores Tβ4 as a developmental peptide used to “remind” adult organs of embryonic regenerative states. PMC
  https://pmc.ncbi.nlm.nih.gov/articles/PMC8228050/

 Clinical Disclaimer

This page summarises clinical research, scientific literature, and experimental findings surrounding TB-500. At The NAD Clinic, peptide therapy is delivered under supervised research-based protocols and is not intended to diagnose, treat, or cure medical conditions.

The Miracle Molecule