Epithalon (Epitalon)

Epithalon (Epitalon)

Longevity Peptide • Telomere Activation • Anti-Aging • Sleep Optimisation • Immune Support

Benefits of Epithalon

 Longevity & Anti-Aging

• Telomere lengthening

• Slower biological aging

• Improved gene expression

• Reduced oxidative stress

 Dramatically Better Sleep

• Increased melatonin

• Deeper REM cycles

• Less night waking

• Improved recovery

 Improved Physical Performance

• Enhanced recovery

• Better mitochondrial output

• Reduced inflammation

 Cognitive & Mood Benefits

• Sharper memory

• Better mood stability

• Improved stress tolerance

• Enhanced mental clarity

 Immune Strengthening

• Fewer infections

• Stronger immune response

• Faster illness recovery

How Epithalon Works (Mechanisms of Action)

 1. Activates Telomerase

• Epithalon stimulates the enzyme telomerase, which lengthens telomeres — the protective caps on our DNA.

  Shorter telomeres =

  • aging

  • higher disease risk

  • reduced cellular function

  Longer telomeres =

  • healthier cells

  • slower aging

  • improved longevity

 2. Regulates Melatonin & Sleep–Wake Cycles

Epithalon restores circadian rhythm by increasing endogenous melatonin production.

Benefits include:

• deeper sleep

• easier sleep onset

• improved morning alertness

• better hormonal balance

 3. Anti-Aging Effects on the Brain

Epithalon supports:

• improved neuroplasticity

• reduced neuroinflammation

• enhanced cognitive function

• better stress resilience

 4. Potent Antioxidant Activity

Epithalon reduces:

• lipid peroxidation

• free radical damage

• cellular oxidative stress

This preserves tissue function and slows biological aging.

 5. Immune System Enhancement

Studies show improvements in:

• T-cell function

• NK-cell activity

• Immune memory

• Resistance to infections

Especially useful for older adults, chronic stress, or lowered immunity.

What Is Epithalon?

Epithalon (also called Epitalon or Epithalamin) is one of the most researched anti-aging peptides.
Originally discovered by Professor Vladimir Khavinson, it is a synthetic tetrapeptide derived from the natural pineal-gland protein epithalamin.

Epithalon is primarily known for its unique ability to:

• Activate telomerase (the enzyme that lengthens telomeres)

• Improve sleep quality via melatonin regulation

• Enhance immune function

• Reduce oxidative stress & cellular aging

• Improve mitochondrial function

• Enhance recovery & vitality

It is one of the few peptides with direct human data showing increased lifespan, improved functional markers, and rejuvenation of gene expression.

Dosage, Injection Volume & Cycling

 Concentration:

50 mg / 10 ml (5 mg/ml)

 Dose:

10 mg daily
= 2 ml SC/IM daily

 Injection Volume:

• 5 mg → 1 ml SC

• 10 mg → 2 ml SC

Synergy Stacks

 Longevity Optimisation

• Epithalon + NAD+ Therapy
  Maximizes mitochondrial, cellular,
  and DNA repair pathways.

 Sleep & Recovery Stack

• Epithalon + Ipamorelin
  Deep restorative sleep + GH
  pulse improvement.

 Anti-Inflammatory Anti-Aging

• Epithalon + Glutathione
  Potent detox + antioxidant synergy.

All treatments include a brief consultation and are supervised by qualified clinicians.

Who Is Epithalon Ideal For?

 Men & Women Over 40

• Slowed recovery

• Reduced vitality

• Sleep disturbances

• Age-related inflammation

 Longevity-Focused Clients

• Biohackers

• Anti-aging enthusiasts

• Preventative health goals

 Those With Poor Sleep Quality

• Light sleepers

• Early waking

• Jet lag

• Shift workers

 Cycle:

10–20 days per cycle
Repeat every 6 months

 Injection Sites:

• Subcutaneous (abdomen or thigh)

• Intramuscular (deltoid/glute)

 Best Injection Time:

• Nighttime injection recommended for sleep synergy

 Performance & Vitality

• Epithalon + CJC-1295 DAC
  Restores hormonal signalling + improves recovery.

 Safety & Side Effects

Epithalon is extremely well tolerated.

Possible temporary effects:

• Mild fatigue

• Transient headache

• Deeper-than-normal sleep

• Increased dreaming (melatonin increase)

• Very mild warmth at injection site

No long-term adverse effects reported.

 High-Stress Professionals

• Burnout

• Dysregulated cortisol

• Fatigue

• Burnout

 Post-Illness or Chronic Fatigue

• Immune dysfunction

• Mitochondrial imbalances

 Epithalon (Epitalon / Epithalamin-related) — Scientific Research & Clinical Studies

• Review of Epitalon & telomere biology (2025) – Summarises evidence that Epitalon can induce telomerase expression, activity and telomere elongation in human somatic cells. PMC
  https://pmc.ncbi.nlm.nih.gov/articles/PMC11943447/

• Melatonin & circadian regulation – Technical review documenting that epithalamin/Epitalon can modulate melatonin production and circadian rhythms, especially in older adults. alzdiscovery.org
  https://www.alzdiscovery.org/uploads/cognitive_vitality_media/Epithalamin-and-Epithalon-Cognitive-Vitality-For-Researchers.pdf

• Summary article on telomerase & anti-aging effects – Overview of Epithalon’s role in telomerase activation, genomic rhythm, and potential lifespan effects (secondary but useful synthesis). Healthspan
  https://www.gethealthspan.com/research/article/epitalon

(Much of the data is cellular/animal; human clinical longevity data remain limited.)

 Clinical Disclaimer

This information summarises decades of clinical research, peer-reviewed publications and endocrine biology. Epithalon is administered at The NAD Clinic under research-based wellness protocols and is not intended to diagnose, treat, or cure disease.

The Miracle Molecule