
GHK-Cu (Copper Peptide)
GHK-Cu (Copper Peptide)
Skin Repair • Collagen Synthesis • Anti-Aging • Tissue Regeneration


Benefits you may feel from NAD+ IV Therapy
Skin & Aesthetic Benefits
Increases collagen I & III
Reduces wrinkles & fine lines
Improves elasticity & skin thickness
Reduces pigmentation & sun damage
Brightens complexion
Minimises pores
Accelerates healing after cosmetic treatments
Reduces appearance of scars & stretch marks
Healing & Regeneration
Improves wound healing
Supports tendon & connective tissue repair
Reduces fibrosis
Improves angiogenesis
Anti-Aging & Longevity
Protects against oxidative stress
Activates DNA repair genes
Supports mitochondrial function
Improves overall cellular health
How GHK-Cu Works (Mechanisms of Action)
1. Activates Over 400 Genes for Repair
GHK-Cu stimulates gene expression related to:
skin remodelling
ECM (extracellular matrix) building
fibroblast activity
keratinocyte repair
angiogenesis
2. Reduces Inflammation
GHK-Cu decreases inflammatory cytokines such as:
TNF-α
IL-6
NF-κB pathway
This results in reduced redness, irritation, swelling, and oxidative stress.
3. Increases Collagen & Elastin
Research shows dramatic increases in:
Type I collagen
Glycosaminoglycans
Integrins
Elastic fibres
This is why it is widely used in anti-aging medicine and cosmetic dermatology.
4. Enhances Wound Healing
GHK-Cu improves:
blood flow
fibroblast migration
tissue remodelling
cellular oxygenation
It is used clinically for burns, surgeries, scars, abrasions, and injuries.
5. Anti-Aging Signalling System
GHK-Cu supports:
stem cell activation
antioxidant pathways
mitochondrial protection
DNA repair gene expression
What Is GHK-Cu?
GHK-Cu is a naturally occurring copper-binding peptide found in the human body, first identified in 1973. It is one of the most scientifically studied regenerative molecules, known for its ability to activate large sets of genes involved in wound healing, collagen synthesis, antioxidant defence, and skin rejuvenation.
As levels decline with age, supplementation provides marked improvements in:
Skin quality & firmness
Healing speed
Inflammation reduction
Collagen & elastin production
Hair growth
Tissue regeneration
GHK-Cu works both topically and systemically, making it one of the most versatile anti-aging peptides available.




Dosage, Injection Volume & Cycling
Concentration:
50 mg / 10 ml (5 mg/ml)
Dose:
2–3 mg daily or every second day
Injection Volume:
2 mg → 0.4 ml SC
3 mg → 0.6 ml SC
Synergy Stacks
Anti-Aging & Skin
GHK-Cu + Epithalon
GHK-Cu + Glutathione
GHK-Cu + NAD+ Therapy
Healing & Recovery
GHK-Cu + BPC-157
GHK-Cu + TB-500
All treatments include a brief consultation and are supervised by qualified clinicians.
Who Is GHK-Cu Ideal For?
GHK-Cu is recommended for clients seeking:
Anti-aging and skin rejuvenation
Faster recovery after cosmetic procedures
Healing for scar tissue
Reduction in inflammation and redness
Enhanced collagen development
Improved hair and follicle health
Long-term cellular regeneration
Suitable for men & women of all ages.
Cycle:
8–12 weeks on → 4 weeks off
Injection Sites:
Abdomen
Upper outer thigh
Upper glute
Back of the arm
Rotate injection sites daily.
Longevity
GHK-Cu + Epithalon + NAD+ + HBOT
Safety & Side Effects
GHK-Cu is extremely well tolerated.
Possible mild effects:
Temporary redness at injection site
Light tingling
Mild skin sensitivity
Avoid use if:
Pregnant or breastfeeding
You have copper metabolism disorders (rare)
GHK-Cu (Copper Peptide) — Scientific Research & Clinical Studies
Regenerative & gene-level actions of GHK-Cu – Review of GHK-Cu’s effects on skin repair, collagen, elastin, glycosaminoglycans, and gene expression related to regeneration and anti-inflammation. PMC+1
https://pubmed.ncbi.nlm.nih.gov/29986520/
https://pmc.ncbi.nlm.nih.gov/articles/PMC6073405/
GHK as a modulator of multiple cellular pathways – Demonstrates GHK-Cu stimulation of collagen synthesis, ECM remodelling, and wound healing across multiple tissues. PMC
https://pmc.ncbi.nlm.nih.gov/articles/PMC4508379/
Topical GHK anti-wrinkle study (2024) – Human cosmetic study showing GHK-Cu and Pal-GHK as effective anti-wrinkle peptides, improving skin quality and collagen support. PubMed
https://pubmed.ncbi.nlm.nih.gov/39963574/
GHK-Cu in self-healing hydrogel for wound repair (2025) – Tripeptide-copper hydrogel enhances collagen/elastin and supports wound healing. PMC
https://pmc.ncbi.nlm.nih.gov/articles/PMC11788471/
Clinical Disclaimer
The information provided on this page is based on scientific literature, clinical research, and published peer-reviewed data. Peptide therapies are used in a clinical, research-based capacity at The NAD Clinic and are not intended to diagnose, treat, or cure medical conditions. All protocols are overseen by qualified practitioners and personalised to each individual's needs.



